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目的探讨液基薄层细胞检测(Thinprep cytologic test,TCT)在妇女宫颈癌前病变筛查中应用。方法回顾分析本院2010年6月—2011年7月TCT患者2 865例,有异常者经阴道镜检查及多点活检证实,以组织病理学诊断为标准进行分析。结果 2 865例TCT患者中,ASC 150例(5.23%),LSIL34例(1.19%),HSIL21例(0.73%),SCC6例(0.21%),HPV感染12例(0.42%),滴虫2例(0.07%),念珠菌16例(0.56%)。结论 TCT作为宫颈病变初筛手段,能够发现大量宫颈癌前病变,结合阴道镜下组织活检,能大大提高宫颈癌前病变的检出率。
Objective To investigate the application of thinprep cytologic test (TCT) in the screening of cervical precancerous lesions in women. Methods A retrospective analysis of our hospital from June 2010 to July 2011 TCT 2,865 cases of patients with abnormalities by colposcopy and multi-point biopsy confirmed by histopathological diagnosis as the standard analysis. Results Among 2 865 patients with TCT, ASC were found in 150 cases (5.23%), LSIL in 34 cases (1.19%), HSIL in 21 cases (0.73%), SCC in 6 cases (0.21%), HPV infection in 12 cases (0.42% (0.07%), Candida 16 (0.56%). Conclusion As a screening method for cervical lesions, TCT can detect a large number of precancerous lesions of the cervix, combined with colposcopic tissue biopsy, can greatly improve the detection rate of cervical precancerous lesions.