论文部分内容阅读
男,50岁,藏族,1986年5月入院。右足第四、五趾坏死脱落,蹠骨外露,感染积脓,手术清除死骨后碘仿纱条填塞,青霉素和链霉素过敏试验分别阴性后肌注抗感染。第二天,全身搔痒乏力、咽干、心慌胸闷。T38℃,P140次/分,BP15.5/10.1kPa,双球结膜水肿明显,全身荨麻疹,心肺未见异常,疑为青霉素或链霉素过敏,停药后口服扑尔敏和非那根抗过敏药物效果不佳。第三天换敷料,见伤口周围皮肤水肿、起疱、糜烂,脓性分泌物较多,继续用碘仿纱条填塞。次日症状加重,尤以咽干咽痛、球结膜水肿及荨麻疹为著,立即更换碘仿纱条,改用氯霉素
Male, 50 years old, Tibetan, admitted to hospital in May 1986. Right foot fourth, five toe necrosis loss, metatarsal exposure, empyema infection, sequestering iodized gauze packing after operation to clear the sequestrum, penicillin and streptomycin allergy test were negative after intramuscular injection of anti-infection. The next day, the whole body itching fatigue, throat, palpitation chest tightness. T38 ℃, P140 beats / min, BP15.5 / 10.1kPa, clear conjunctival edema, systemic urticaria, heart and lung no abnormalities, suspected of penicillin or streptomycin allergy, Allergy drugs do not work well. Dress dressing for the third day, see the skin around the wound edema, blisters, erosion, purulent secretions more, continue to use iodoform gauze packing. The next day the symptoms worsened, especially pharyngeal sore throat, conjunctival edema and urticaria for the immediate replacement of iodoform gauze, switch to chloramphenicol