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目的:评价参松养心胶囊对特发性室性早搏(IPVCs)不同早搏负荷患者窦性心率震荡(HRT)的影响。方法:按不同早搏负荷,将94例IPVCs患者分为高负荷组30例、中负荷组36例、低负荷组28例,比较各组参松养心胶囊治疗前后HRT参数震荡初始(TO)和震荡斜率(TS)变化。结果:三组治疗后,低负荷组TO、TS无明显改善(P>0.05),高、中负荷组TO、TS均有明显改善(P均<0.05),尤以高负荷组改善更显著。结论:参松养心胶囊能改善IPVCs高、中早搏负荷患者的HRT,早搏负荷越重其改善程度越佳;HRT改善程度可作为药物治疗IPVCs的疗效衡量指标。“,”Objective: To explore the effect of heart rate turbulence (HRT) in patients with different degree load of idiopathic premature ventricular contractions (IPVCs) after Shengsongyangxin capsule therapy. Methods: A total of 94 patients with IPVCs was divided into three groups by the load of contractions in different degrees: high-load group(n=30), moderate-load group(n=36)and low-load group(n=28), compared the change in values of turbulence onset (TO) and turbulence slope (TS) of HRT parameters amongst different groups before and after Shengsongyangxin capsule treatment. Results: There were significantly improved of TO and TS of the moderate-load and high-load groups, compared to pre therapy (P0.05). Conclusions: Shengsongyangxin capsule therapy could improve the HRT of patients with moderate-load or high-load IPVCs,the larger the load, the more the improvement; The scale of improvement of HRT could be a good maker to assess the effectiveness of drug for the treatment of IPVCs.