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食管切除是治疗食管癌的主要手段,食管癌术后5年生存率为30.0%~45.0%~([1]),超过50.0%食管癌术后患者上消化道功能异常,这些变化不可避免地对患者生活质量乃至长期生存造成影响。尽管采取一些手术方法如幽门成形、抗反流吻合等,可以改善上述功能紊乱,但疗效并不理想。本文旨在总结食管癌术后上消化道功能紊乱的病理生理学变化和临床表现,并评价现有治疗方法的疗效及其对生活质量的影响。
Esophagectomy is the main treatment of esophageal cancer, 5-year survival rate of esophageal cancer after 30.0% ~ 45.0% ~ ([1]), more than 50.0% of esophageal cancer patients with upper gastrointestinal dysfunction, these changes inevitably On the quality of life of patients and even long-term impact. Although some surgical methods such as pyloroplasty, anti-reflux anastomosis, can improve these disorders, but the effect is not satisfactory. This article aims to summarize the pathophysiological changes and clinical manifestations of postoperative upper gastrointestinal disorders in esophageal cancer, and to evaluate the efficacy of existing therapies and their impact on quality of life.