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目的:探讨老年高血压患者脉压(pp)与心率减速力关系。方法:对150例老年高血压患者进行动态血压检测,根据脉压(pp)分为三组,A组60例(pp<40mm Hg),B组47例(40mm Hg≤pp≤60mm Hg),C组43例(pp>60mm Hg),所有患者行动态心电图,离线分析后计算出心率减速力(DC值)、心率变异性(HRV)时域指标,三组间进行比较分析。结果:C组与A组比较DC值、NN间期标准差(SDNN)、NN间期平均值的标准(SDANN)、相邻NN间期差值的均方差(r MSSD)均显著降低(P<0.05),C组与B组比较DC值、SDNN、SDANN、r MSSD均降低(P<0.05),B组与A组比较DC值、SDNN、SDANN、r MSSD均降低(P<0.05)。结论:老年高血压脉压与DC值及HRV呈负相关,对高血压患者不仅降低血压,更要缩小脉压,减小自主神经功能损害。
Objective: To investigate the relationship between pulse pressure (pp) and heart rate deceleration in elderly hypertensive patients. Methods: The ambulatory blood pressure was measured in 150 elderly hypertensive patients. The patients were divided into three groups according to pulse pressure (pp): group A (n = 60), group B (n = 47) Group C (n = 43) (p> 60mm Hg). All patients underwent dynamic electrocardiogram. After offline analysis, the decelerated heart rate (DC) and the heart rate variability (HRV) were calculated and compared between the three groups. Results: Compared with group A, DC value, SDNN, SDANN of NN, and rMSSD of adjacent NN were all significantly decreased (P (P <0.05). The values of DC, SDNN, SDANN and MSSD in group C and group B decreased (P <0.05). The values of DC, SDNN, SDANN and r MSSD in group B and group A decreased (P <0.05). Conclusion: The pulse pressure of elderly patients is negatively correlated with DC and HRV. It not only reduces blood pressure, but also reduces pulse pressure and decreases autonomic nerve dysfunction.