定量图像分析在前列腺癌预后评估中的意义

来源 :临床泌尿外科杂志 | 被引量 : 0次 | 上传用户:djmaxha
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为寻找可评估前列腺癌对激素依赖性和前列腺癌患者预后的病理诊断量化指标,采用电子计算机图像分析仪,选择9顶几何参数作为定量诊断指标,对激素治疗后生存不满3年和超过3年的两组前列腺癌病例的病理切片进行定量图像分析。结果核面积、核周长、核直径、核圆度因子等指标在两病例组间有显著性差异。认为定量图像分析有助于对前列腺癌雄激素依赖性的识别、治疗的选择和预后的评估。 To find quantitative indexes for pathological diagnosis that can evaluate the prognosis of prostate cancer patients with hormone-dependent and prostate cancer, computerized image analyzer was used to select nine geometric parameters as quantitative diagnostic indicators. After survival of hormone therapy for less than 3 years and more than 3 years The pathological sections of the two groups of prostate cancer cases were subjected to quantitative image analysis. Results There were significant differences in the nuclear area, nuclear perimeter, nuclear diameter, and nuclear roundness factor between the two groups. Quantitative image analysis is believed to contribute to the androgen-dependent recognition of prostate cancer, the choice of treatment, and the assessment of prognosis.
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