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间质性肾炎是指以肾间质病变为突出表现的肾脏疾病。肾间质为分布在肾小球及肾小管以外的结缔组织,皮质部分的间质组织稀疏,髓质部分的间质较为紧密,尤其是锥体尖端部。以往由于光镜所见病理组织学的相似性,常把肾盂肾炎与间质性肾炎作为同义词或将两者混为一谈。根据近10年来的研究,认为间质性肾炎是由许多不同原因所引起的疾病,其病变除在间质之外,肾小管几乎同时受累。因此,近年来部分学者提议用“肾小管间质性肾炎”这个名词。间质性肾炎按其病理形态及临床表现不同可分为急性及慢性两大类。
Interstitial nephritis is a renal disease characterized by renal interstitial lesions. Interstitial renal interstitial distribution in the glomerular and tubular connective tissue outside the cortical part of the interstitial tissue sparse, medulla part of the interstitial more closely, especially the tip of the cone. In the past due to the histopathological similarities seen in light microscopy, often pyelonephritis and interstitial nephritis as a synonym or confused with the two. According to nearly 10 years of research, interstitial nephritis is considered to be caused by many different diseases, the lesions in addition to interstitial tubules almost simultaneously. Therefore, in recent years some scholars proposed the use of the term “tubulointerstitial nephritis”. Interstitial nephritis according to their pathological morphology and clinical manifestations can be divided into two categories of acute and chronic.