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目的观察步长脑心通胶囊治疗老年冠心病的临床疗效。方法选取2014年1月—2016年5月中国医科大学附属盛京医院收治的老年冠心病患者100例,根据治疗方法分为对照组和观察组,每组50例。对照组患者采用常规治疗,观察组患者在常规治疗基础上口服步长脑通心胶囊;两组患者均治疗1个疗程(4周为1个疗程)。比较两组患者临床疗效及治疗前后血清同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)及N-末端脑钠肽前体(NT-pro BNP)水平。结果观察组患者临床疗效优于对照组(P<0.05)。治疗前两组患者血清Hcy、hs-CRP及NT-pro BNP水平比较,差异无统计学意义(P>0.05);治疗后观察组患者血清Hcy、hs-CRP及NT-pro BNP水平低于对照组(P<0.05)。治疗后两组患者血清Hcy、hs-CRP及NT-pro BNP水平均低于治疗前(P<0.05)。结论步长脑心通胶囊治疗老年冠心病的临床疗效确切,可有效改善患者心功能,减轻炎性反应。
Objective To observe the clinical effect of BuXiaoNaoXinTong capsule on senile coronary heart disease. Methods From January 2014 to May 2016, 100 elderly patients with coronary heart disease admitted to Shengjing Hospital of China Medical University were divided into control group and observation group with 50 cases in each group. The patients in the control group were treated with conventional therapy. The patients in the observation group were given oral stepngongtongxin capsule on the basis of conventional treatment. Both groups were treated for 1 course (4 courses for 1 course). The clinical efficacy and the levels of serum homocysteine (Hcy), hs-CRP and NT-pro BNP before and after treatment were compared between the two groups. Results The clinical efficacy of the observation group was better than that of the control group (P <0.05). The levels of serum Hcy, hs-CRP and NT-pro BNP in the two groups before treatment were not significantly different (P> 0.05). The levels of Hcy, hs-CRP and NT-pro BNP in the observation group were lower than those in the control group Group (P <0.05). Serum Hcy, hs-CRP and NT-pro BNP levels in both groups after treatment were lower than those before treatment (P <0.05). Conclusion Buchang Naoxintong capsule is effective in treating elderly patients with coronary heart disease, which can effectively improve the cardiac function and reduce the inflammatory reaction.