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目的观察麝香保心丸与硫氮唑酮治疗心脏X综合征的临床疗效。方法选择心脏X综合征患者72例,随机分为麝香保心丸组(42例)及硫氮唑酮组(30例),比较两组患者治疗半年后症状及心电图运动试验结果。结果麝香保心丸组总有效率为90%,较硫氮唑酮组的60%高(P<0.05)。两组患者治疗后运动时间明显延长(P<0.05),运动ST段压低>0.1mV的持续时间明显缩短(P<0.05),麝香保心丸治疗组缩短更明显(P<0.05)。结论麝香保心丸可明显缓解心脏X综合征患者的临床症状,提高患者的运动耐力,缩短运动时心肌缺血时间。疗效优于钙通道阻断剂硫氮酮。
Objective To observe the clinical efficacy of Shexiang Baoxin Pills and dithiocarb for the treatment of Cardiac X syndrome. Methods Seventy-two patients with cardiac syndrome X were randomly divided into three groups: the “Shexiang Baoxin Pill” group (42 cases) and the thiazolidone group (30 cases). The symptoms and electrocardiogram test results were compared between the two groups after six months of treatment. Results The total effective rate of Shexiang Baoxin Pill group was 90%, which was higher than that of the other groups (P <0.05). The exercise duration was significantly prolonged in both groups (P <0.05), and the duration of ST segment depression> 0.1mV was significantly shortened (P <0.05). The SHI treatment group was shorter (P <0.05). Conclusion Shexiang Baoxin Pill can significantly relieve the clinical symptoms of patients with cardiac X syndrome, improve exercise tolerance and shorten myocardial ischemic time during exercise. Efficacy than calcium channel blocker diazinone.