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应用硫酸锌、复合蛋白锌对环磷酰胺引起的小鼠脾脏及胸腺重量变化的影响进行了观察。结果表明，胸腺微量元素锌含量高于脾脏，复合蛋白锌组胸腺重量及其指数高于环磷酰胺组（Ｐ＜０．０５），与硫酸锌组无差异（Ｐ＞０．０５）．脾脏指数与环磷酰胺组相比亦有差异（Ｐ＜０．０５）。复合蛋白锌组胸腺和脾脏重量及指数均高于硫酸锌组。提示锌剂在减少环磷酰胺引起的胸腺和脾脏损伤方面具有一定作用。
The effects of zinc sulfate and zinc complex protein on the weight changes of spleen and thymus in mice induced by cyclophosphamide were observed. The results showed that the content of zinc in thymus was higher than that in spleen. The weight and index of thymus in composite protein zinc group were higher than that in cyclophosphamide group (P <0.05), but no difference with zinc sulfate group (P> 0.05). Spleen index and cyclophosphamide group also have differences (P <0.05). The weight and index of thymus and spleen of composite protein zinc group were higher than those of zinc sulfate group. Suggesting that zinc has a role in reducing the damage of thymus and spleen caused by cyclophosphamide.