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酮康唑为咪唑类抗真菌药 ,常用剂型多为洗剂 [1] 、霜剂[2 ] 等。这些制剂的渗透作用较弱 ,影响药物疗效。根据临床需要 ,我们将酮康唑与适量的地塞米松制成复方酊剂 ,并建立含量测定方法 ,进行了稳定性试验。1 材料与方法1 .1仪器 UV- 8458紫外分光光度计 (惠普公司 ,USA)
Ketoconazole is an imidazole antifungal agent, lotion commonly used lotion [1], cream [2] and so on. The infiltration of these formulations is weak, affecting drug efficacy. According to the clinical needs, we will ketoconazole with appropriate amount of dexamethasone compound tincture, and the establishment of the content determination method, the stability test. 1 Materials and methods 1.1 Instrument UV-8458 UV spectrophotometer (Hewlett-Packard, USA)