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目的:探讨CT和MRI在嗅神经母细胞瘤的诊断、分期及疗后随诊中的价值。材料和方法:回顾性复习10例嗅神经母细胞瘤的CT扫描和1例MRI的表现。男6例,女5例。年龄13~65岁,中位年龄32岁。临床表现为鼻堵、鼻衄各6例,眼外突4例,偏头痛、视力下降、鼻翼肿物各2例。CT平扫5例,增强扫描6例;横断面8例,冠状面7例。MRI为SE序列,T1和T2加权像,并用Gd-DTPA作增强扫描。6例有随诊CT,1例有随诊MRI。结果:按Kadish分期标准:A期1例,B期2例,C期8例。侵犯范围为鼻腔11例,同侧筛窦、眼眶各6例,蝶窦、上颌窦、前颅凹内各4例,鼻翼软组织2例。CT增强扫描6例中5例为中度不均质强化,1例为高度强化。MRIT1加权像呈中、低信号,T2加权像呈中、高信号。结论:嗅神经母细胞瘤的影像学表现无特异性。影像学检查目的为界定肿瘤侵犯范围。冠状面扫描有助于显示颅内、眶内病变,必不可少。MRI的T2加权像有助于鉴别肿瘤和鼻窦内积液,在界定肿瘤范围方面优于CT。疗后的基线所见和定期随诊影像学检查有助于检出复发,及时行补救治疗
Objective: To investigate the value of CT and MRI in the diagnosis, staging and follow-up of patients with olfactory neuroblastoma. Materials and Methods: A retrospective review of 10 cases of olfactory neuroblastoma CT scan and 1 case of MRI findings. 6 males and 5 females. Aged 13 to 65 years old, the median age of 32 years. Clinical manifestations of nasal obstruction, epistaxis in 6 cases, 4 cases of extraocular surgery, migraine, decreased visual acuity, nasal alveolar tumor in 2 cases. CT scan in 5 cases, enhanced scan in 6 cases; 8 cross-section, coronal in 7 cases. MRI was SE sequence, T1 and T2 weighted images, and enhanced scanning with Gd-DTPA. 6 cases were followed up CT, 1 case was followed up MRI. Results: According to Kadish staging criteria: 1 case in stage A, 2 cases in stage B and 8 cases in stage C. Infringement range of 11 cases of nasal cavity, ipsilateral ethmoid sinus, orbital in 6 cases, sphenoid sinus, maxillary sinus, anterior cranial fossa in 4 cases, 2 cases of nasal soft tissue. Five of the 6 cases of CT enhanced scanning were moderately inhomogeneous and 1 was highly advanced. MRIT1 weighted image was medium and low signal, T2 weighted image was medium and high signal. Conclusion: The imaging findings of olfactory neuroblastoma are nonspecific. The purpose of imaging examination is to define the extent of tumor invasion. Coronal scan helps to show intracranial orbital lesions, indispensable. MRI T2 weighted images help identify tumors and sinus fluid, in defining the scope of the tumor is better than CT. Post-treatment baseline findings and regular follow-up of imaging studies can help detect recurrence and promptly remedial treatment