急性心肌梗塞(下称心梗)时给予β受体阻滞剂可降低血清心肌酶水平,减轻梗塞型心电图改变,减少临床并发症,防止演变为完全梗塞,以上表明该药可能限制梗塞范围。本文作者等组织一次协作试验,在心梗症状开始4小时内,按体重给心得安5～8mg,5分钟静脉注射完毕;以后1小时、3小时、继以每4小时口服心得安40mg/剂,27小时共服320mg。对于有哮喘史,并有需用支气管扩张剂的支气管炎、心衰、呼吸困难,伴有广泛肺湿性罗音、收缩压 Administration of a beta-blocker to acute myocardial infarction (hereafter referred to as MI) reduces serum myocardial enzyme levels, decreases infarction-type electrocardiogram changes, reduces clinical complications and prevents progression to complete infarction, all of which indicate that the drug may limit infarct size. The authors and other organizations a collaborative trial, within 4 hours of onset of myocardial infarction symptoms, according to the body weight to propranolol 5 ~ 8mg, 5 minutes intravenous injection; 1 hour later, 3 hours, followed by 4 hours per oral propranolol 40mg / , 27 hours total serving 320mg. For patients with a history of asthma and bronchitis requiring bronchodilators, heart failure, dyspnea, and extensive pulmonary rales, systolic pressure