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目的探讨立止血与奥美拉唑联合治疗新生儿消化道出血的临床疗效。方法回顾性分析2010年2月-2012年2月我院收治的59例消化道出血的新生患儿的临床资料,根据治疗方法分为治疗组和对照组,治疗组采用立止血和奥美拉唑联合治疗,对照组仅采用立止血进行治疗,比较治疗后两组患儿的临床疗效。结果治疗3d后,治疗组的总有效例数为29例,占93.55%,显著高于对照组的21例(75.00%),P<0.05;治疗组黑便消失、隐血试验阴性和胃引流无血的平均时间均显著少于对照组(P<0.05)。结论采用立止血与奥美拉唑联合治疗新生儿消化道出血,能缩短患儿黑便消失、隐血试验阴性和胃引流无血的平均时间,临床疗效显著。
Objective To investigate the clinical efficacy of combination of hemostatic and omeprazole in the treatment of neonatal gastrointestinal bleeding. Methods The clinical data of 59 neonates with gastrointestinal hemorrhage admitted from February 2010 to February 2012 in our hospital were retrospectively analyzed. According to the treatment methods, the patients were divided into treatment group and control group, Azole combination therapy, the control group only treated with standing blood, comparing the clinical efficacy of two groups of children after treatment. Results After 3 days of treatment, the total effective cases in the treatment group were 29 cases (93.55%), significantly higher than that in the control group (21 cases, 75.00%), P <0.05; the melena disappeared, the occult blood test was negative and the gastric drainage did not The average blood time was significantly less than the control group (P <0.05). Conclusions The combination of ophthalmone and omeprazole in the treatment of neonatal gastrointestinal bleeding can shorten the average time of disappearance of melena in children, negative occult blood test and no bleeding after gastric drainage. The clinical curative effect is significant.