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66例DN患者随机分为对照组给予常规治疗,观察组在常规治疗的基础上加用阿魏酸钠0.3g/d,疗程为2周。治疗前后分别检测24 h尿蛋白定量(TP/24h)、血肌酐(Scr)、尿素氮(BUN)。结果:治疗后TP/24h、Scr、BUN明显降低(P<0.05或P<0.01)。结论:阿魏酸钠可明显改善糖尿病肾病患者的肾功能状态,减少尿蛋白。
66 cases of DN patients were randomly divided into control group given conventional treatment, the observation group on the basis of conventional treatment with sodium ferulate 0.3g / d, treatment for 2 weeks. 24 h urine protein (TP / 24h), serum creatinine (Scr) and blood urea nitrogen (BUN) were measured before and after treatment. Results: The levels of Scr and BUN in TP / 24h after treatment were significantly decreased (P <0.05 or P <0.01). Conclusion: Sodium ferulate can significantly improve renal function and reduce urinary protein in patients with diabetic nephropathy.