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目的了解医学生过敏性疾病发病与生命早期生活因素的关系,为开展过敏性疾病的早期预防提供参考。方法以2009年温州医学院2 042名一～三年级学生为对象,采用回顾性调查表进行问卷调查,收集出生时相关情况、家族史相关情况及5个生长发育时期过敏性疾病的发病情况。应用SPSS 16.0进行二元Logistic回归分析。结果医学生出生时情况中的出生地、出生体重、出生时成熟情况、性别与过敏性疾病有关;在家族史中的父母过敏性疾病史、受教育程度、职业及父亲吸烟史等与各年龄段过敏性疾病发病相关性较高。结论父母受教育程度、暴露于烟雾环境、出生体重轻、早产是过敏性疾病的易感因素,应针对其开展相应干预研究。
Objective To understand the relationship between the incidence of allergic diseases and early life factors in medical students and provide references for the early prevention of allergic diseases. Methods A total of 2,042 first to third graders from Wenzhou Medical College in 2009 were recruited. Retrospective questionnaires were used to investigate the incidence of family history and the incidence of allergic diseases at birth. Binary logistic regression analysis was performed using SPSS 16.0. Results At birth, birth weight, birth weight, maturity at birth and gender were related to allergic diseases. The incidence of allergic diseases such as parents ’history of parents, educational attainment, smoking history and fathers’ Segment allergic disease incidence is higher. Conclusions Parents’ educational level, exposure to smog environment, low birth weight and premature delivery are the predisposing factors for allergic diseases. Corresponding intervention studies should be carried out.