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目的：探讨原发鼻腔NK/T细胞淋巴瘤的发病情况、临床特点、治疗方案及疗效。方法回顾性分析苏州大学附属第一医院2007年1月～2013年4月收治的鼻腔NK/T细胞淋巴瘤患者45例。结果45例患者均行同期放化疗，其中6例患者后续接受造血干细胞移植。26例患者治疗后达到完全缓解，5年生存率（OS）和无进展生存率（PFS）分别为58.0%、57.2%，ⅠE～ⅡE期分别为64.0%、63.6%，Ⅲ～Ⅳ期为29.2%、30.0%。结论同期放、化疗可有效治疗鼻腔NK/T细胞淋巴瘤，自体造血干细胞移植可进一步改善生存。“,”Objective To evaluate the incidence, clinical features and treatment of primary nasal NK/T-cell lymphoma (NK/TL). Methods The data of 45 patients diagnosed as NK/TL between January 2007 and April 2013 were reviewed. Results All patients completed concurrent chemoradiotherapy (CCRT), 6 patients were treated with stem cell transplantation after CCRT (5 patients autologous hematopoietic stem cell transplantation [AHSCT] and 1 patient cord blood transplantation). After treatment, 26 of 45 patients achieved complete response (CR). The 5-year overall survival (OS) and the progress free survival (PFS) were 58.0%and 57.2%respectively. The 5-year OS and PFS of patients in stageⅠE~ⅡE were 64.0%and 63.6%, which were significantly higher than that of patients in stageⅢ~Ⅳ(29.2%and 30.0%), P<0.05. Conclusion CCRT could be effective in treating primary nasal NK/TL, and AHSCT should be considered in improving the survival further.