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口腔溃疡(canker sore)是口腔黏膜最易罹患的疾病,其发病率在口腔疾病中仅次于龋病和牙周病,占第3位。口腔复发性阿弗他溃疡(recurrent aphthous ulcer,RAU)是最常见的口腔黏膜病,普通人群的发病率为20%左右,其病因复杂,存在明显的个体差异[1]。目前公认的病因有免疫因素、遗传因素、系统性疾病因素、感染因素、环境因素、氧自由基因素、微循环障碍等[2]。近年来,食物过敏引起RAU在国外一些研究中有所报道,现综述如下。
Oral ulcer (canker sore) is the most prone to oral mucosa disease, the incidence of oral diseases in the second only to dental caries and periodontal disease, No. 3. Oral recurrent aphthous ulcer (RAU) is the most common oral mucosal disease. The incidence of the common population is about 20%. Its etiology is complex and there are obvious individual differences [1]. Currently recognized causes of immune factors, genetic factors, systemic disease factors, infection factors, environmental factors, oxygen free radicals, microcirculation [2]. In recent years, food allergy caused RAU in some foreign studies have been reported, are summarized below.