With the increasing diversity of application needs and computing units, the server with heterogeneous pro-cessors is more and more widespread. However, conventional SMP/ccNUMA server architecture introduces communication bottleneck between heterogeneous processors and only uses heterogeneous processors as coprocessors, which limits the e?ciency and flexibility of using heterogeneous processors. To solve this problem, this paper proposes an intra-server inter-connect fabric that supports both intra-server peer-to-peer interconnection and I/O resource sharing among heterogeneous processors. By connecting processors and I/O devices with the proposed fabric, heterogeneous processors can perform direct communication with each other and run in stand-alone mode with shared intra-server resources. We design the proposed fabric by extending the de-facto system I/O bus protocol PCIe (Peripheral Computer Interconnect Express) and implement it with a single chip cZodiac. By making full use of PCIe’s original advantages, the interconnection and the I/O sharing mechanism are light weight and e?cient. Evaluations that have been carried out on both the FPGA (Field Programmable Gate Array) prototype and the cycle-accurate simulator demonstrate that our design is feasible and scalable. In addition, our design is suitable for not only the heterogeneous server but also the high density server.