阿奇霉素联合口服泼尼松治疗支原体肺炎临床观察

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目的:探究阿奇霉素联合口服泼尼松治疗支原体肺炎的效果。方法:选取广东省佛山市南海区人民医院2015年1月至2016年12月儿科收治的50例支原体肺炎患者,随机分为研究组及对照组,各25例,对照组患者给予口服阿奇霉素治疗,研究组患者在对照组基础上加用口服泼尼松治疗,比较两组患者咳嗽消失时间、退热时间、不良反应发生情况及临床治疗总有效率。结果:经治疗后,研究组患者咳嗽消失时间及退热时间明显短于对照组,差异具有统计学意义(P<0.05),比较两组患者不良反应发生率,差异无统计学意义(P>0.05),研究组患者临床治疗总有效率显著高于对照组,差异具有统计学意义(P<0.05)。结论:临床采用阿奇霉素联合口服泼尼松治疗支原体肺炎疗效显著,可快速改善患者咳嗽症状,退热迅速,同时患者耐受性好,安全可靠。 Objective: To investigate the effect of azithromycin combined with oral prednisone in the treatment of mycoplasma pneumonia. Methods: Fifty cases of Mycoplasma pneumonia admitted from Nanhai District People’s Hospital of Foshan City, Guangdong Province from January 2015 to December 2016 were randomly divided into study group and control group, each with 25 cases. Patients in the control group were treated with oral azithromycin, Patients in the study group were treated with oral prednisone on the basis of the control group. The duration of cough disappearance, the time of fever, the incidence of adverse reactions and the total effective rate of clinical treatment were compared between the two groups. Results: After treatment, the cough disappear time and the antipyretic time in the study group were significantly shorter than those in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). The total effective rate of clinical treatment in study group was significantly higher than that in control group, the difference was statistically significant (P <0.05). Conclusion: The clinical effect of azithromycin and oral prednisone in the treatment of mycoplasma pneumonia is obvious. It can quickly improve the cough symptoms and the rapid fever relief in patients. At the same time, the patients are well tolerated and safe.
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