非甾体类抗炎药(NSAIA)用于肾脏疾病的治疗,迄今已有20余年。对其疗效及副作用,至今仍有争议。70年代中期,许多学者报道 NSAIA 可使肾病综合征病人蛋白尿明显减少,而风靡一时,广泛应用。时至80年代,不少人发现许多肾综病人在使用NSAIA 后,蛋白尿虽减少,但停药后很快复发,更有甚者,部分病例在用药过程中,出现肾小球滤过率 Non-steroidal anti-inflammatory drugs (NSAIA) have been used in the treatment of kidney disease for more than 20 years. Its efficacy and side effects are still controversial. In the mid-1970s, many scholars reported that NSAIA can significantly reduce the proteinuria in patients with nephrotic syndrome, while the rage, widely used. When the 80s, many people found that many patients with renal comprehensive treatment of NSAIA, although proteinuria decreased, but relapse soon after stopping, what is more, in some cases in the course of medication, the occurrence of glomerular filtration rate