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目的探讨用指端末梢血检测糖化血红蛋白(HbA1c)的临床应用。方法检测2型糖尿病患者末梢血和全血中的HbA1c,并用健康体检者作对照组。对15例糖尿病患者在全天不同时间取末梢血检测HbA1c,与早晨空腹结果进行比较。结果用指端末梢血在稀释模式下与用静脉全血在全血模式下检测HbA1c结果 ,差异无统计学意义(P=0.11)。28.86%的2型糖尿病患者血糖控制水平理想,32.99%控制一般,38.14%控制效果差。同一天内不同时间用末梢血检测HbA1c与早晨空腹的结果差异无统计学意义(P>0.05)。结论用末梢血检测HbA1c可用于糖尿病的监控。
Objective To investigate the clinical application of detecting peripheral blood hemoglobin (HbA1c). Methods HbA1c in peripheral blood and whole blood of patients with type 2 diabetes mellitus was detected and used as control group. HbA1c was measured in peripheral blood of 15 diabetic patients at different times of the day and compared with morning fasting results. Results There was no significant difference in the results of HbA1c test between the peripheral blood of the finger tip and the whole blood of the venous whole blood in the dilution mode (P = 0.11). 28.86% of type 2 diabetes patients with good blood glucose control level, 32.99% control in general, 38.14% poor control. There was no significant difference in the results of HbA1c and morning fasting on the same day at different times (P> 0.05). Conclusion The detection of peripheral blood HbA1c can be used for the monitoring of diabetes.