论文部分内容阅读
本文报告单用阿苯达唑(ABZ)和阿苯达唑合并亚砜(ABZ·SO)对体外培养的细粒棘球绦虫原头节的杀灭作用。用美蓝排斥试验和感染小鼠的方法评定原头节的存活力,用透射电镜和扫描电镜观察药物对原头节超微结构的影响。 细粒棘球蚴原头节系无菌取自屠宰绵羊的肝包囊,试验前用美蓝排斥试验测定其活力,并将原头节在37℃下含青霉素和链霉素的199培养液内培养。单用ABZ或ABZ·SO和二者按1:1混合溶于1:100O二甲亚砜(DMSO)内,加培养液使终浓度为
This article reports the killing effect of abamectin (ABZ) and albendazole combined with sulfoxide (ABZ · SO) on the protoscoleces of Echinococcus granulosus cultured in vitro. The viability of primate was evaluated by methylene blue exclusion test and mouse infestation, and the effect of prodrugs on the ultrastructure of proroca was observed by transmission electron microscopy and scanning electron microscopy. Echinococcus granulosus aseptic joints were taken from slaughtered sheep liver cysts before the test with methylene blue exclusion test to determine its activity and the original head section at 37 ℃ with penicillin and streptomycin 199 broth Internal culture. ABZ alone or ABZ · SO and the two were mixed 1: 1 in 1: 100O dimethylsulfoxide (DMSO), add the medium to a final concentration of