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目的探讨老年肺癌非手术治疗患者医院内获得性肺炎的临床特点及对策。方法对2006年1月至2008年12月住院的275例非手术治疗老年肺癌的医院内获得性肺炎(Hospital-acquired pneumonia,HAP)情况进行回顾性分析。结果本组病例发生院内获得性肺炎165例。以中央型肺癌、鳞癌易发院内获得性肺炎;由革兰阴性菌导致的HAP明显高于革兰阳性菌与真菌;放疗加化疗HAP感染率高于单纯放疗或化疗;随着白细胞下降,感染率明显增高,特别是粒细胞<1.0×109/L者感染率最高。结论根据老年肺癌非手术治疗院内获得性肺炎的临床特点把HAP的预防作为根本措施,一旦出现感染应及时治疗。
Objective To investigate the clinical characteristics and countermeasures of hospital-acquired pneumonia in non-surgical treatment of elderly patients with lung cancer. Methods A retrospective analysis of hospital-acquired pneumonia (HAP) in 275 non-surgical elderly patients with lung cancer hospitalized from January 2006 to December 2008 was performed. Results In this group of patients with nosocomial pneumonia in 165 cases. HCC caused by Gram-negative bacteria was significantly higher than that of Gram-positive bacteria and fungi. The infection rate of HAP in radiotherapy plus chemotherapy was higher than that of radiotherapy or chemotherapy alone. With the leukopenia, Infection rate was significantly higher, especially granulocytes <1.0 × 109 / L, the highest infection rate. Conclusion According to the clinical characteristics of non-surgical treatment of nosocomial pneumonia in elderly patients with HAP prevention as a fundamental measure, once the infection should be treated promptly.