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目的：比较阴道给米索前列醇与静脉滴注缩宫素对足月引产的有效性及安全性。方法：５０例产妇（初产妇４９例、经产妇１例）年龄２０～４０ａ，妊娠３７．６～４２．４ｗｋ，随机分为２组，各２５例。Ａ组用米索前列醇１片（５０μｇ／片）阴道给药，４～６ｈ重复直至临产。Ｂ组用静脉滴注缩宫素２．５～５ＩＵ。结果：用药后６ｈＡ组比Ｂ组宫颈Ｂｉｓｈｏｐ评分改善更明显（Ｐ＜０．０５）；从给药引产到阴道分娩的时间短，但无统计学差异（１１±５ｈｖｓ１５±７ｈ，Ｐ＞０．０５）；引产成功率高（８８％ｖｓ４４％，Ｐ＜０．０１）；２组均未发现明显副作用。结论：阴道给米索前列醇较静脉滴注缩宫素足月引产的成功率高。
OBJECTIVE: To compare the efficacy and safety of vaginal administration of misoprostol with intravenous oxytocin on full-term induced labor. Methods: Fifty mothers (49 primiparages and one maternal one) aged 20-40 years and 37.6-42.4 weeks were randomly divided into 2 groups (n = 25). A group with misoprostol 1 (50μg / tablets) vaginal administration, 4 ~ 6h repeat until labor. B group with intravenous oxytocin 2.5 ~ 5IU. Results: The Bishop score of 6hA group improved more obviously than that of group B (P <0.05). The time from administration of induction of labor to vaginal delivery was short, but there was no statistical difference (11 ± 5hvs15 ± 7h, P> 0). 05). The success rate of induction of labor was high (88% vs44%, P <0.01). No obvious side effects were found in both groups. Conclusion: The vaginal delivery of misoprostol has a higher success rate of full-term induction of oxytocin than intravenous oxytocin.