目的了解溶栓继发脑出血的临床表现及CT特点。方法回顾性分析血栓栓塞性疾病应用溶栓继发脑出血的11例患者的的临床和CT资料。结果本组溶栓继发的脑出血10例患者发生在溶栓后的24h内,且以5～10h多见(6例),临床特点为病情重、预后差,死亡5例;CT显示血肿形状不规则,出血量较多,4例为多灶性脑出血,有9例血肿破入脑室或/和蛛网膜下腔,病灶分布以脑叶多见,主要为颞、顶叶。结论溶栓后的24h内应特别注意观察神经功能的变化,溶栓同时进行抗凝、抗血小板聚集治疗及溶栓药剂量较大可能是导致继发脑出血的重要因素,且临床表现及CT所见与高血压性脑出血有所不同。 Objective To understand the clinical manifestations and CT features of cerebral hemorrhage secondary to thrombolysis. Methods The clinical and CT data of 11 patients with thrombotic thromboembolism who underwent thrombolysis secondary to intracerebral hemorrhage were retrospectively analyzed. Results 10 cases of intracerebral hemorrhage secondary to thrombolysis occurred in 24h after thrombolysis and were more common in 5 to 10 hours (6 cases). The clinical features were severe illness, poor prognosis and death in 5 cases. CT showed hematoma Irregular shape, more bleeding, 4 cases of multifocal intracerebral hemorrhage, 9 cases of hematoma broken into the ventricle or / and subarachnoid space, the lesion is more common in the brain lobe, mainly in the temporal and parietal lobes. Conclusion 24h after thrombolysis should pay special attention to changes in neurological function, thrombolysis at the same time anticoagulant, antiplatelet aggregation therapy and thrombolytic drugs larger doses may be an important factor leading to secondary cerebral hemorrhage, and clinical manifestations and CT See and hypertensive intracerebral hemorrhage is different.