本文介绍一种比较适合于教学、科研工作的,简便、可靠的实验模型。 一、材料与万法 选择体重2kg左右的健康雄性家兔3只,每只经耳缘静脉注入致病性大肠杆菌内毒素250μg(大肠杆菌内毒素O_(111)B_4,上海生物制品研究所生产,每支1,000μg,加蒸馏水10ml,抽取2.5ml即含内毒素250μg)。24小时后,以同一剂量,再从兔耳静脉注入一次。每次注射后观察其表现并做记录。第二 This article introduces a simple, reliable experimental model that is more suitable for teaching and research work. I. Materials and methods A total of 3 healthy male rabbits weighing about 2 kg were selected and injected with 250 μg of pathogenic E. coli endotoxin via the ear vein (E. coli endotoxin O_(111)B_4, produced by Shanghai Institute of Biological Products). , Each 1,000μg, add distilled water 10ml, extract 2.5ml containing endotoxin 250μg)). After 24 hours, the same dose was injected once again from the rabbit ear vein. Observe their performance and record each injection. second