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用失血性休克大鼠离体心脏研究了促甲状腺素释放激素（Ｔｈｙｒｏｔｒｏｐｉｎ－ＲｅｌｅａｓｉｎｇＨｏｒｍｏｎｅ，ＴＲＨ）对肾上腺素能α，β，多巴胺（ＤＡ）受体激动剂正性肌力作用及β－内啡肽负性肌力作用的影响。结果表明ＴＲＨ可增强肾上腺素能β－受体及多巴胺受体激动剂的正性肌力作用，拮抗β－内啡肽的负性肌力作用，提示ＴＲＨ对休克大鼠心脏β－和ＤＡ受体具有一定的增敏作用，ＴＲＨ的抗休克作用与其增敏β－和ＤＡ受体，增加它们对其受体激动剂的反应性及拮抗β－内啡肽的心血管抑制作用有关。
The effects of Thyrotropin-Releasing Hormone (TRH) on the positive inotropic effect of adrenergic α, β, dopamine receptor agonists and β-endorphin Negative effects of muscle strength. The results showed that TRH could enhance the positive inotropic effect of adrenergic beta-receptors and dopamine receptor agonists and antagonize the negative inotropic effects of beta-endorphin, suggesting that TRH can inhibit the beta and d The body has a sensitizing effect. The anti-shock effect of TRH is related to the increase of their receptors for β-and DA receptors, their reactivity to their receptor agonists and the antagonism of the cardiovascular inhibition of β-endorphin.