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细胞因子在糖尿病发病中的作用逐渐受到人们的重视。细胞因子信号转导抑制物(suppressors of cytokine signaling,SOCS)可抑制细胞因子在细胞内的信号转导,并对糖尿病的发病和发展起着一定的促进作用。此外,SOCS蛋白也参与胰岛素抵抗和瘦素抵抗的发生和发展。
The role of cytokines in the pathogenesis of diabetes gradually attracted people’s attention. Suppressor of cytokine signaling (SOCS) can inhibit cytokines in the cell signal transduction, and the onset and development of diabetes play a role in promoting. In addition, SOCS protein is also involved in the occurrence and development of insulin resistance and leptin resistance.