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目的:观察中药复方调脂降糖汤联合辛伐他汀与单用辛伐他汀治疗高脂血症合并代谢综合征患者的疗效。方法:120例病人随机分为治疗组60例、对照组60例,于用药前及用药4周和8周测定总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)。结果:服药4、8周,两组比较效果有显著性差异(P<0.01),且治疗组可缩短达标时间。结论:复方调脂降糖汤联合辛伐他汀治疗高脂血症合并代谢综合征疗效优于单用辛伐他汀。
Objective: To observe the curative effect of traditional Chinese medicine compound Tiazhi Jiangtang Decoction combined with simvastatin and simvastatin alone on patients with hyperlipidemia and metabolic syndrome. Methods: 120 patients were randomly divided into treatment group (60 cases) and control group (60 cases). The levels of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL- C), low-density lipoprotein cholesterol (LDL-C). Results: 4 and 8 weeks after taking the medicine, there was a significant difference between the two groups (P <0.01), and the treatment group could shorten the time of reaching the standard. Conclusion: Compound Tiaozhi Jiangtang Decoction combined with simvastatin treatment of hyperlipidemia with metabolic syndrome is superior to simvastatin alone.