目的探讨小儿手足口病的临床诊治措施。方法回顾分析260例患者的临床资料。结果本组显示,手足口病好发于<3岁儿童尤其是婴幼儿,男性发病率明显高于女性。患儿经治疗后皮疹均基本消退,体温正常,食欲好转,平均6d基本痊愈出院。合并心肌损害、血糖升高患儿亦恢复正常。对具有高危因素的15例重症患儿进行严密监测,早期使用丙种球蛋白及甲基强的松龙治疗后,均获痊愈,住院时间平均8d,未再进展为危重症而发生死亡。结论倡导普及病原学检查,对提高疾病的认识及了解流行状态具有重要意义,给临床医生提供更准确的监测信息。 Objective To investigate the clinical diagnosis and treatment of hand-foot-mouth disease in children. Methods The clinical data of 260 patients were retrospectively analyzed. Results This group shows that hand-foot-mouth disease occurs in children <3 years old, especially infants and young children, the incidence was significantly higher in males than females. Children with the treatment of rash basically subsided, normal body temperature, appetite improved, the average recovery of 6d basically discharged. Combined myocardial damage, elevated blood sugar also returned to normal children. 15 critically ill children with high risk factors were closely monitored. After treatment with gamma globulin and methylprednisolone, all patients were cured. The average length of hospital stay was 8 days, with no further progressing to critical illness and death. Conclusions The promotion of universal etiological examination is of great importance to raising awareness of the disease and understanding the epidemic situation, and provides clinicians with more accurate monitoring information.