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夫西地酸为一种具有甾体骨架的抗生素,其化学结构与头孢菌素P相似。主要通过抑制细菌蛋白质的合成而起抗菌作用。本药对革兰阳性菌及奈瑟球菌、结核杆菌有较强抗菌活性;对链球菌属(包括肺炎双球菌)和棒状杆菌也有一定抗菌活性。本药对多数革兰阴性菌无效。临床上用于敏感菌(尤
Fusidic acid is a steroid skeleton of antibiotics, its chemical structure and cephalosporin P similar. Antibacterial effect mainly through the inhibition of bacterial protein synthesis. The drug on Gram-positive bacteria and Neisseria, Mycobacterium tuberculosis has strong antibacterial activity; Streptococcus (including pneumococcus) and coryneform bacteria also have some antibacterial activity. The drug is not effective against most Gram-negative bacteria. Clinically used for sensitive bacteria (especially