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本研究综述了自1959年以来国内外发生的人感染H7亚型禽流感事件。大多数是在家禽爆发禽流感期间,农场工人在处置感染鸡群过程中被暴露而感染;也有曾接触活禽或曾到过活禽市场而感染;有经禽流感病毒致病的哺乳动物(海豹)感染于人或实验室感染(事故)所致。引起人感染的H7亚型中已知有H7N2、H7N3、H7N7以及2013年在中国发现的新的致病亚型H7N9。H7N2、H7N3、H7N7感染以结膜炎为主,大多为轻症;而H7N9感染以严重的呼吸道感染为特征,表现为重症肺炎,呼吸窘迫综合症,病死率高达33.6%。
This study summarizes the human cases of H7 subtype AIV that have occurred since 1959 at home and abroad. Most are infected with farm workers exposed during the treatment of infected flocks during the bird flu outbreak in poultry; others have been exposed to live poultry or have been to the live poultry market; mammals that have been challenged by the bird flu virus ( Seal) infection in people or laboratory infections (accident) caused. H7N2, H7N3, H7N7 and the new pathogenic subtype H7N9, which was discovered in China in 2013, are known among the H7 subtype causing human infection. H7N2, H7N3 and H7N7 infections are mainly conjunctivitis, mostly mild; while H7N9 infection is characterized by severe respiratory infection, showing severe pneumonia and respiratory distress syndrome with a mortality rate of 33.6%.