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目的 分析视网膜静脉阻塞患者的血液流变学改变 ,探讨其发病机制 .方法 视网膜静脉阻塞患者 40 (男 2 0 ,女 2 0 )例 ,与相同例数的可以与之相匹配的正常对照组男、女各 2 0例进行血液流变学检查及统计学处理 ,并根据眼底荧光血管造影图像中有无毛细血管无灌注区及临床表现的严重程度分组 .结果 患者组明显高于对照组 (P <0 .0 5或 P<0 .0 1 )的项目有 :低切粘度、高切粘度、血浆粘度、全血还原比粘度、纤维蛋白原 .血液流变学各项指标增高程度与有无毛细血管无灌注无关 .结论 高血粘度与视网膜静脉阻塞的发生密切相关 ,但其程度与视网膜静脉阻塞的严重程度无关 .
Objective To analyze the changes of hemorheology in patients with retinal vein occlusion and to explore its pathogenesis.Methods Forty (male 20, female 20) patients with retinal vein occlusion were divided into two groups with the same number of matched normal controls , And 20 female patients underwent hemorheological examination and statistical analysis.According to the presence or absence of capillary perfusion region and the severity of clinical manifestations in fundus fluorescein angiography images, the results were significantly higher in patients than in control group (P <0. 0 5 or P <0. 0 1) items are: low shear viscosity, high shear viscosity, plasma viscosity, whole blood reduction viscosity, fibrinogen. Hemorheology various indicators of the increase and the presence of Capillary perfusion was not related.Conclusion Hyperviscosity is closely related to the occurrence of retinal vein occlusion, but its extent has nothing to do with the severity of retinal vein occlusion.