胺碘酮是苯丙呋喃的衍化物,起初用以治疗冠状动脉病变患者的心绞痛,事实上,本药作为抗心绞痛药物仅有中等度的疗效。以后的经验提示,胺碘酮能有效地治疗室上性和室性快速心律失常。胺碘酮的抗心律失常作用在停药后可持续30到45天。胺碘酮可非竞争性地阻断α和β肾上腺素能受体,可 Amiodarone is a derivative of benzofuran originally used to treat angina pectoris in patients with coronary artery disease. In fact, the drug has only a modest effect as an anti-anginal drug. Later experience suggests that amiodarone is effective in the treatment of supraventricular and ventricular tachyarrhythmia. The antiarrhythmic effect of amiodarone lasts for 30 to 45 days after discontinuation. Amiodarone blocks alpha and beta adrenergic receptors non-competitively