Soft tissue sarcoma ( STS ) refers to a category of malignancies with mesenchymal origin, they might occur in all sites of human body but account for only 1% of all human cancers. With the development of modern techniques in diagnosis and treatment, as well as the emergence of new anti-sarcoma agents and the implication of multidisciplinary treatment, the prognosis of STS has been signiifcantly improved. Most of STS patients are currently treated in specialized cancer centers with standardized treatment, while some are treated in orthopedic department or general surgery department of general hospitals, which might lead to misdiagnostics and mistherapeutics. The unplanned surgical treatment for STS is caused by inattention or ignorance of the importance of standard treatment. It has an incidence of 18%-59% from literatures and is very common in the country. Here addressed is a brief introduction of misdiagnostics and mistherapeutics of STS. The most important factor is how we can prevent an unplanned treatment.