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作者根据血浆在凝固和溶解过程中由液态→胶体→液态时在光密度上产生显著变化的特性,用分光光度计和电子电位差计自动描绘此变化的过程,得到一曲线图,——纤维蛋白溶解活性动态图。该图可同时反应血浆凝固时间、程度及凝块溶解时间等三个参数,并能计算出纤维蛋白的含量。用它观察慢性肝炎、尿毒症和急性心肌梗塞等疾病以及急性心肌梗塞患者治疗过程中纤溶系统活性的变化,结果比较满意.作者认为本方法操作简便、重复性好、反应灵敏、节省时间,凡在反应过程中光密度产生变化者均可应用,有推广价值。
The authors automatically plot the change process using a spectrophotometer and an electronic potentiometer to obtain a graph based on the characteristics of significant changes in optical density of the plasma during solidification and dissolution from liquid to colloidal to liquid state, Dynamic picture of proteolytic activity. The figure can simultaneously reflect the three parameters of plasma coagulation time, extent and clot lysis time, and can calculate the content of fibrin. Use it to observe the changes of fibrinolytic system activity in chronic hepatitis, uremia and acute myocardial infarction and acute myocardial infarction patients, the results are satisfactory.The author thinks the method is simple, good repeatability, responsive, time-saving, Where the changes in optical density during the reaction can be applied, there is a promotional value.