厚皮性骨膜增生病(Pachy dermoperiostosis)是一综合征,亦称原发性或特发性肥大性骨关节病(Primary or idiopathic hyperfrophic osteoarthropathy),或称Touraine-Solente-Gole综合征,此病少见,报告二例如下: 例1:女,15岁。患者于生后即发现指趾粗大;一岁半时前囱闭合;10岁以后四肢长骨进行性增粗,两侧膝关节和踝关节肿 Pachy dermoperiostosis is a syndrome, also known as Primary or idiopathic hyperfrophic osteoarthropathy, or Touraine-Solente-Gole syndrome, a rare disease , Two cases are as follows: Example 1: Female, 15 years old. Patients found that after the birth of the toe is thick; aged one and a half hours before the chimney closed; 10 years after the long bones of the limbs thickening, knee and ankle on both sides of the swollen