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目的观察呼出气一氧化氮(Fe NO)测定对老年哮喘的诊断和疗效评估的作用。方法选取50例老年支气管哮喘患者作为哮喘组,另选50例非呼吸系统疾病老年患者作为对照组,对比两组进行一氧化氮测定结果。结果哮喘组入院时的一氧化氮水平明显高于对照组,差异有统计学意义(P<0.05);治疗1、2周及随访2个月后哮喘组患者一氧化氮水平明显低于入院时,差异有统计学意义(P<0.05,P=0.001,P=0.003)。结论老年哮喘患者呼出气一氧化氮值显著升高,呼出气一氧化氮测定检测在老年哮喘患者诊断和疗效评估中起着重要的作用。
Objective To observe the role of exhaled nitric oxide (NO) determination in the diagnosis and evaluation of senile asthma. Methods Fifty elderly patients with bronchial asthma were selected as the asthma group and another 50 elderly patients with non-respiratory diseases were selected as the control group. Nitric oxide was compared between the two groups. Results The levels of nitric oxide in the asthma group were significantly higher than those in the control group (P <0.05). The levels of nitric oxide in the asthma group were significantly lower than those in the asthma group at 1, 2, and 2 months after treatment , The difference was statistically significant (P <0.05, P = 0.001, P = 0.003). Conclusion The value of nitric oxide in exhaled breath of elderly patients with asthma is significantly increased. The measurement of exhaled nitric oxide plays an important role in the diagnosis and efficacy evaluation of senile asthma patients.