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ＤＣＣ基因位于人类染色体 1 8ｑ2 1 .3 ,在 88%结肠癌、直肠癌患者中 ,ＤＣＣ基因的表达明显减少或缺失。为了评价ＤＣＣ基因在白血病发病及骨髓增生异常综合征 (ＭＤＳ)转化为白血病的作用 ,我们检测了 3 1例白血病患者和 8例ＭＤＳ患者的ＤＣＣ基因表达情况。病例和方法1
The DCC gene is located on the human chromosome 18q21.3, in 88% of colon cancer, rectal cancer patients DCC gene expression was significantly reduced or missing. To assess the role of DCC in leukemia and the conversion of myelodysplastic syndrome (MDS) to leukemia, we examined DCC gene expression in 31 leukemia patients and 8 MDS patients. Case and method 1