目的　探讨酒精灭活再植并游离腓骨植入治疗股骨远端恶性肿瘤的可行性。方法　我们回顾了自1999年6月至2 0 0 2年5月以来在我科诊治的10例股骨远端恶性骨肿瘤病例。手术方法采用瘤段酒精灭活,腓骨填充再植术。结果　平均随访3年4个月(11个月～6年)。8例无复发,7例膝关节活动范围达6 0°～90°,1例发生感染。结论　结果提示本保肢手术在治疗恶性骨肿瘤中是切实可行的,并可达到较高的成功率。 Objective To investigate the feasibility of alcohol inactivated replantation and free fibula implantation in the treatment of distal femoral malignancies. Methods We reviewed 10 cases of distal femoral malignant bone tumors treated in our department from June 1999 to May 2002. Surgical methods using tumor alcohol inactivation, fibular replantation. Results The average follow-up of 3 years and 4 months (11 months to 6 years). 8 cases without recurrence, 7 cases of knee range of motion 6 0 ° ~ 90 °, 1 case of infection. Conclusion The results suggest that the limb salvage surgery in the treatment of malignant bone tumors is feasible and achievable a high success rate.