成人腹泻轮状病毒(ADRV)已被证实是引起成人感染性腹泻的主要病原体。ADRV最初是从我国兰州和锦州的流行性腹泻暴发中分离到的。目前,部分流行病学研究报道,ADRV抗体阳性率在英国是4—10％,澳大利亚是15％,美国是9.5％;但也有报告在我国以外的其它国家,ADRV阳性率小于1％,在我国是4—53％。现有的检测ADRV抗原、抗体的诊断试剂均采用粪便做为抗原,故其敏感性特异性较差。我们报告了ADRV第5基因的克隆,该基因主要编码的内壳蛋白,命名VP6。ADRV抗体可 Adult diarrhea rotavirus (ADRV) has been identified as the major causative agent of adult infectious diarrhea. ADRV was originally isolated from an outbreak of epidemic diarrhea in Lanzhou and Jinzhou in our country. At present, some epidemiological studies have reported that the positive rates of ADRV antibodies are 4-10% in the UK, 15% in Australia and 9.5% in the United States. However, other countries outside of China have reported that the positive rate of ADRV is less than 1% Is 4-53%. Existing detection of ADRV antigen, antibody diagnostic reagents are used as an antigen, so the sensitivity of its poor specificity. We report the cloning of the fifth gene of ADRV, which encodes mainly the endoprotein, named VP6. ADRV Antibody