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脊椎动物胚胎发育过程中,经卵裂和囊胚期积累了一定数量的细胞后,在原肠期开始出现明显的细胞运动,囊胚表层的细胞通过一个称为组织者(Spemann and Mongald’sorganizer)的结构进入胚胎的内部,经过内陷、内卷、汇聚、延伸等一系列细胞运动,按照既定的方向迁移到达目的地,参与构建各个胚层,这一过程称为形态发生运动。形态发生运动是脊椎动物胚胎发育必不可少的重要步骤,在这一过程中,特定的单个细胞或成群细胞的定向迁移,对于三个胚层(外胚层、中胚层、内胚层),以及由这些胚层所产生的特定组织器官的发育与分化,具有决定性影响。
During the process of embryogenesis in vertebrates, after a certain number of cells have been accumulated in the cleavage and blastocyst stages, significant cell motility begins to occur in the gastrula stage, and the cells in the surface layer of the blastocyst are differentiated through a process known as Spemann and Mongald’sorganizer Of the structure into the embryo’s internal, after a series of cell movement such as invagination, involute, convergence, extension, in accordance with the established direction of migration to reach their destination, involved in the construction of the germ layer, the process known as morphogenetic movement. Morphogenesis is an essential step in the vertebrate embryo development. In this process, the targeted migration of specific single cells or clusters of cells, for the three germ layers (ectoderm, mesoderm, endoderm) The development and differentiation of specific tissues and organs produced by these germ layers have a decisive influence.