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心力衰竭是各种心脏疾病的终末阶段,有很高的病死率和病残率,因此早期诊断、正确评价心功能、判断预后,以便及时治疗非常重要。心脏脂肪酸结合蛋白是一种可溶性的小分子细胞内非酶蛋白质,主要存在于心室中,心肌细胞缺血缺氧时释放到血浆中,血浆中升高程度与心功能级别呈正相关,可早期诊断心力衰竭及评价心功能严重程度,在各种类型心脏疾病中均有应用,在心力衰竭的诊断及评价中具有较高的特异性和敏感性,本文作简要综述。
Heart failure is the terminal stage of a variety of heart diseases, high mortality and morbidity, early diagnosis, correct evaluation of cardiac function, prognosis, in order to timely treatment is very important. Cardiac fatty acid-binding protein is a soluble small molecule non-enzymatic protein in cells, mainly in the ventricle, myocardial ischemia and hypoxia release into the plasma, the plasma level of elevation and cardiac function was positively correlated, early diagnosis Heart failure and evaluation of the severity of cardiac function, in all types of heart disease have applications, in the diagnosis and evaluation of heart failure with high specificity and sensitivity, this article briefly reviewed.