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目的 探讨期乳腺癌术后放疗对生存率和局部复发率的影响。方法 对比分析期乳腺癌术后行放疗者150例(放疗组)与手术后未行放疗者191例(手术组),未作胸壁照射。结果 放疗组和手术组总的8年生存率和局部复发率为46.0%、55.0%(P>0.05)和4.0%、10.5%(P<0.05)。腋淋巴转移≥4个,放疗组与手术组8年生存率为36.9%、11.1%(P<0.05);腋淋巴转移1～3个和≥4个,放疗组和手术组局部复发率为1.5%、10.2%(P<0.05)和6.2%、22.2%(P<0.05)。两组胸壁复发率最高。结论 (1)腋淋巴转移4个以上,术后放疗可显著提高生存率;(2)腋淋巴转移病人,术后放疗可降低野内复发,建议高危胸壁复发病人加照胸壁
Objective To investigate the effect of postoperative radiotherapy for breast cancer on the survival rate and local recurrence rate. Methods Compared with the control group, 150 cases of radiotherapy (radiotherapy group) and 191 cases of radiotherapy group (operation group) after radiotherapy were operated without breast wall irradiation. Results The overall 8-year survival and local recurrence rates were 46.0%, 55.0% (P> 0.05) and 4.0%, 10.5% (P <0.05) respectively in the radiotherapy group and the operation group. The axillary lymphatic metastasis was more than 4, the 8-year survival rate was 36.9%, 11.1% (P <0.05) in radiotherapy group and operation group, 1 to 3 and 4 in axillary lymph node metastasis, and the local recurrence rate in radiotherapy group and operation group was 1.5 %, 10.2% (P <0.05) and 6.2%, 22.2% (P <0.05) respectively. The highest rate of chest wall recurrence in both groups. Conclusions (1) More than 4 axillary lymph node metastases, postoperative radiotherapy can significantly improve the survival rate; (2) patients with axillary lymph metastasis, postoperative radiotherapy can reduce the recurrence in the field, the proposed high-risk chest wall recurrence patients with chest wall