论文部分内容阅读
性状青霉烷砜为青霉素基核衍生物。化学上是磺酸青霉素钠,灰白色粉品,易溶于水,分子量为255.22。氨苄青霉素得自6-氨基青霉烷酸,化学上是D(-)-a—氨苄青霉素,分分子量为371.39。优立新为青霉烷砜和氨苄青霉素的组合物,为小瓶装配制用干粉。分别相当于1000+2000,500+1000,250+500,125+250毫克青霉烷砜和氨苄青霉素,联装盒则分别含有1000+2000,500+1000,250+500毫克青霉烷砜和氨苄青霉素。作用青霉烷砜虽不具备任何抗菌能力(萘瑟氏菌除外),生化研究已证实,它是耐青霉素菌所含β-内酰胺酶的不可逆抑制剂。青霉烷砜对防止抗药性菌株破坏青霉素的能力,业经耐药性菌株微生物整体研究证
Character Penicillin sulfone penicillin-based nuclear derivatives. Chemically, sodium penicillin sulfonate, gray powder products, soluble in water, a molecular weight of 255.22. Ampicillin was obtained from 6-aminopenicillanic acid, chemically D (-) - a-ampicillin with a molecular weight of 371.39. You Li new penicillins and ampicillin composition for the assembly of small bottles with dry powder. Equivalent to 1000 + 2000, 500 + 1000, 250 + 500, 125 + 250 mg penicillin and ampicillin, respectively, and cartridges containing 1000 + 2000, 500 + 1000, 250 + 500 mg penicillin and ampicillin . Although penicillin sulfone does not possess any antibacterial activity (except for Neisseria gonorrhoeae), biochemical studies have confirmed that it is an irreversible inhibitor of β-lactamase contained in penicillin-resistant bacteria. Penicillin sulfone to prevent drug-resistant strains of the ability to destroy penicillin, the strain of microorganisms in the overall study of resistant strains