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目的探讨血清尿酸水平与血压的相关性。方法将5917例健康志愿者分为三组:正常血压组(≤120/80mmHg,921例)、高血压前期组(SBP 120~139mmHg和/或DBP 80~89mmHg,2363例)和高血压组(≥140/90mmHg,2633例),检测血清尿酸水平,分析血压和血清尿酸水平的关系。结果高血压组血清尿酸水平高于高血压前期组,高血压前期组高于正常血压组(P<0.01)。血清尿酸可独立影响SBP(β=0.12,P<0.01)、DBP(β=0.07,P<0.01)和MAP(β=0.12,P<0.01)。结论血清尿酸是血压水平的独立影响因素。对高血压病患者,降压治疗的同时应加强对血清尿酸水平的控制。
Objective To investigate the relationship between serum uric acid and blood pressure. Methods 5917 healthy volunteers were divided into three groups: normotensive group (≤120 / 80mmHg, n = 921), prehypertensive group (SBP 120 ~ 139mmHg and / or DBP 80 ~ 89mmHg, ≥140 / 90mmHg, 2633 cases), serum uric acid levels were measured, the relationship between blood pressure and serum uric acid levels was analyzed. Results The level of serum uric acid in hypertension group was higher than that in the prehypertension group and the prehypertension group was higher than that in the normal blood pressure group (P <0.01). Serum uric acid could independently affect SBP (β = 0.12, P <0.01), DBP (β = 0.07, P <0.01) and MAP (β = 0.12, P <0.01). Conclusion Serum uric acid is an independent factor of blood pressure. For hypertensive patients, antihypertensive treatment should be strengthened at the same time the control of serum uric acid levels.