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目的 :研究穿琥宁注射液与临床常用 2 4种药物配伍的稳定性。方法 :考察穿琥宁注射液与 2 4种药物在室温下配伍后外观、pH、微粒和紫外吸收度。结果 :穿琥宁注射液与庆大霉素、丁氨卡那霉素、环丙沙星、氧氟沙星配伍产生沉淀 ,与VitC、VitB6 、ATP、辅酶A、胞二磷胆碱、氨茶碱、氢化考的松、地塞米松、三氮唑核苷、阿昔洛韦、双黄连、青霉素钠、氨苄西林钠、红霉素、头孢唑啉钠、头孢哌酮钠、头孢曲松钠、头孢呋辛钠、甲硝唑、替硝唑配伍无显著变化。结论 :穿琥宁注射液不宜与庆大霉素、丁氨卡那霉素、环丙沙星、氧氟沙星配伍 ,可与其他 2 0种药物配伍应用
Objective: To study the stability of compatibility of Chuanhuning injection with 24 commonly used drugs in clinical practice. Methods: To observe the appearance, pH, microparticles and UV absorbance of Chuanhuning injection and 24 drugs at room temperature. Results: Chuanhuning injection and gentamicin, amikacin, ciprofloxacin, ofloxacin compatibility precipitation, and VitC, VitB6, ATP, coenzyme A, citicoline, aminophylline , Hydrocortisone, dexamethasone, ribavirin, acyclovir, shuanghuanglian, penicillin sodium, ampicillin sodium, erythromycin, cefazolin sodium, cefoperazone sodium, ceftriaxone sodium, cefuroxime Sodium, metronidazole, tinidazole compatibility no significant change. Conclusion: Chuanhuning injection should not be mixed with gentamicin, amikacin, ciprofloxacin and ofloxacin, and can be used in combination with other 20 kinds of drugs