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根据表皮生长因子(EGF)及绒毛膜促性腺激素(hCG)均具有种间同源性的特点,运用小鼠体内试验及人绒毛组织体外培养模型两种手段,研究EGF与hCG在体内的相互调节作用。结果表明一定剂量范围内的hCG可促进小鼠EGF的合成与释放,同样EGF也可增强人绒毛组织的分泌。提示:EGF与hCG之间可能存在某种正反馈作用。
According to the characteristics of both epidermal growth factor (EGF) and human chorionic gonadotropin (hCG), we used in vitro and in vivo models of human chorionic villi in vitro and in vivo to study the relationship between EGF and hCG in vivo Regulatory effect. The results show that a certain dose of hCG can promote EGF synthesis and release in mice, the same EGF can also enhance the secretion of human chorionic tissue. Tip: There may be some positive feedback between EGF and hCG.