为了解河南省麻疹疫苗 (MV)免疫效力 ,进而探讨麻疹爆发的原因 ,选择 2 0 0 2年 5起有代表性的麻疹爆发 ,进行 1∶2配对的病例对照研究 ,共调查 10 1对。分别根据不同的免疫史来源 ,计算配比与非配比下的MV效力。结果显示 :病例组的MV接种率非常显著地低于对照组。配比后得出的MV效力高于不配比得出的结果。仅凭预防接种记录 ,不考虑家长回忆得出的MV效力为 71 9% ;将家长回忆作为免疫史判断依据得出的MV效力为 89 4 % ,不同免疫史判断标准得出的MV效力均偏低。因此 ,MV效力不够高和免疫接种率偏低是麻疹爆发的主要原因。 In order to understand the immunization efficacy of measles vaccine (MV) in Henan Province, and to explore the causes of the outbreak of measles, five representative measles outbreaks were selected in 2002, and a case-control study of 1: 2 matching was conducted. According to different sources of immune history, calculate the ratio of non-matching and MV effectiveness. The results showed that: MV vaccination rate of the case group was significantly lower than the control group. The MV effect after matching is higher than that of the unmatched result. Only vaccination records, regardless of parents recall the MV effectiveness of 71 9%; parents recall as a basis for judging the immune MV derived from the effectiveness of 89 4%, different immunological criteria to determine the MV derived from the average efficacy low. Therefore, MV ineffectiveness and low immunization rates are the major causes of measles outbreaks.